Company Filing History:
Years Active: 2024
Title: Innovating Stem Cell Cultivation: The Contributions of Leng Leng Chng
Introduction: Leng Leng Chng is a notable inventor based in Singapore, recognized for her pioneering work in the field of biotechnology. She has made significant contributions to the development of a thermoresponsive microcarrier system, which plays a crucial role in advancing stem cell research.
Latest Patents: Leng Leng Chng holds a patent for a "Thermoresponsive Microcarrier System and Uses Thereof." This innovative polymeric microsphere comprises a thermally responsive monomer, specifically N-isopropylacrylamide (NIPAM), crosslinked with a functional group monomer that includes carboxylic acid or amine functional groups. The microspheres are also enhanced with a coating of polymerized catecholamines like DOPA. This groundbreaking patent outlines a method for preparing the microspheres and their applications in culturing, harvesting, or expanding stem cells or stromal cells. Importantly, the technology aims at allowing the expansion or harvesting of human mesenchymal stem/stromal cells (hMSCs) in a serum-free and xeno-free medium, which is vital for ethical stem cell research.
Career Highlights: Leng Leng Chng is affiliated with the Agency for Science, Technology and Research (A*STAR), where she leverages her expertise in developing innovative solutions within the scientific community. Her work focuses on enhancing stem cell cultivation techniques, which can potentially transform therapeutic practices in regenerative medicine.
Collaborations: In her professional journey, Leng Leng Chng collaborates with esteemed colleagues such as Jackie Y. Ying and Daniele Zink. Together, they contribute to advancing scientific research and innovation, fostering a collaborative environment that emphasizes the importance of teamwork in achieving breakthroughs.
Conclusion: Leng Leng Chng's contributions to the field of biotechnology and her patented thermoresponsive microcarrier system signify a remarkable advancement in stem cell research. Her work not only innovates methodologies but also paves the way for more ethical and effective practices in biological research. With her ongoing involvement at A*STAR and collaborative spirit, she continues to impact the scientific landscape significantly.