Len Stephens is a notable inventor based in Sawston, GB, recognized for his significant contributions to the field of biochemistry and molecular biology. With a total of eight patents to his name, he has made substantial advancements in understanding and manipulating key biological processes.

Latest Patents

Among his latest patents, one focuses on Phosphoinositide 3-kinases (PI3K). This invention relates to PI3K crystals, polypeptide muteins, polypeptide fragments, and antibodies. It also includes nucleic acids coding for these polypeptides, methods of modifying PI3Kγ activity, and methods of modulating PI3Kγ activity. The patent encompasses polypeptides and methods related to phospholipid binding, lipid kinase activity, and modulating Ras activity in activating PI3Kγ. Additionally, it addresses the binding of PI3Kγ to cell membranes and modulating protein-protein interactions with PI3Kγ. Another significant patent involves compositions and methods for identifying PKB kinase inhibitors, which are useful for assaying compounds that affect PKB kinase activity, with medical applications for diagnosing and treating diseases.

Career Highlights

Len Stephens has had a distinguished career, working with prominent organizations such as Onyx Pharmaceuticals, Inc. and The Babraham Institute. His work has been pivotal in advancing research in the pharmaceutical and biotechnology sectors.

Collaborations

Throughout his career, Len has collaborated with esteemed colleagues, including Phillip Thomas Hawkins and Sylvia Braselmann. These collaborations have further enriched his research and contributions to the field.

Conclusion

Len Stephens exemplifies the spirit of innovation in the scientific community, with his patents reflecting a deep understanding of complex biological mechanisms. His work continues to influence the development of therapeutic strategies in medicine.

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