Company Filing History:
Years Active: 2006-2010
Title: Leeying Wu: Innovator in Protein Kinase Research
Introduction
Leeying Wu is a prominent inventor based in Lexington, MA (US). She has made significant contributions to the field of protein kinase research, holding a total of 5 patents. Her work focuses on the modulation of apoptosis and the development of novel methodologies employing human protein kinases.
Latest Patents
One of her latest patents is titled "Methods of modulating apoptosis using inhibitors of brain-localized protein kinases homologous to homeodomain-interacting protein kinases." This invention provides isolated protein kinase polypeptides related to novel brain-localized protein kinases homologous to known homeodomain-interacting protein kinases (HIPKs). The invention includes isolated nucleic acid molecules that encode these polypeptides, inhibitors, and related methods. The novel polypeptides and nucleic acid molecules are termed HIPK4. Additionally, the invention provides genetically engineered expression vectors, host cells, and transgenic animals comprising the novel nucleic acid molecules. It also includes antisense and RNAi molecules, as well as inhibitors, activators, and antibodies capable of binding to the protein kinase polypeptides. The invention further explores the uses of HIPK4 and its inhibitors for the modulation of apoptosis, prevention, and treatment of neurological disorders and cancers.
Another significant patent is titled "Compositions, organisms and methodologies employing a novel human kinase." This invention provides compositions, organisms, and methodologies that utilize a novel human protein kinase, HPK3P23. The novel human kinase has sequence homology to the catalytic domains of several protein kinases. The gene encoding this novel protein kinase is localized in or near the 3p23 locus of the human chromosome 3. The sequence similarity indicates that the novel human protein may function as a protein kinase.
Career Highlights
Leeying Wu is currently associated with Wyeth, where she continues her innovative research. Her work has garnered attention in the scientific community for its potential applications in treating various diseases.
Collaborations
Leeying has collaborated with notable coworkers, including Wei Liu and Roger Ford, contributing to her research and development efforts.
Conclusion
Leeying Wu is a distinguished inventor whose work in protein kinase research has the potential to impact the treatment of neurological disorders and cancers. Her innovative patents reflect her commitment to advancing