Leena M Ala-Kokko

Title: Leena M Ala-Kokko: Innovator in Genetic Research

Introduction

Leena M Ala-Kokko is a prominent inventor based in Philadelphia, PA (US). She has made significant contributions to the field of genetic research, particularly in understanding collagen-related disorders. With a total of 7 patents, her work has paved the way for advancements in diagnostic methods for various pathological conditions.

Latest Patents

One of her latest patents focuses on compositions and methods for detecting altered COL1A1 gene sequences. This invention describes methods useful for determining whether a subject has an alteration in a gene encoding a protein chain of Type I or Type IX collagen. The patent outlines novel intronic sequences of five human genes: COL1A1, COL1A2, COL9A1, COL9A2, and COL9A3. It also provides methods for determining the existence of pathological conditions associated with altered genes, including diseases such as osteoporosis, osteoarthritis, and osteogenesis imperfecta. Additionally, her work includes primers and methods for detecting mutations in the procollagen II gene.

Career Highlights

Leena has worked at Thomas Jefferson University, where she has contributed to various research projects. Her innovative approaches have led to significant advancements in the understanding of genetic predispositions to collagen-related disorders.

Collaborations

Throughout her career, Leena has collaborated with notable professionals in her field, including Darwin J Prockop and Andrzej Fertala. These collaborations have further enhanced her research and the impact of her inventions.

Conclusion

Leena M Ala-Kokko's contributions to genetic research and her innovative patents have made a lasting impact on the field. Her work continues to influence diagnostic methods for collagen-related disorders, showcasing her dedication to advancing medical science.