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For the Inventor, By the Inventor

Philadelphia, PA, United States of America

Leena M Ala-Kokko

This inventor holds 7 USPTO granted patents. Top assignees: Thomas Jefferson University, Other. Active years: 1991-2001.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Leena M Ala-Kokko. Retrieved from https://idiyas.com/inventor/leena-m-ala-kokko

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 7

% Patents Active = 100.0

Average Co-Inventor Count = 6.1

ph-index = 4

Forward Citations = 53(Granted Patents)


Location History:

  • Toivontie, FI (1995)
  • Philadelphia, PA (US) (1991 - 1997)
  • Andalusia, PA (US) (1996 - 1999)
  • Oulu, FI (2001)

Company Filing History:

goldMedal6 out of 539 
 
Thomas Jefferson University
 patents
silverMedal1 out of 834,570 
Other
 patents

Years Active: 1991-2001

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7 patents (USPTO):Explore Patents
1. 6265157 - Compositions and methods for detecting altered COL1A1 gene sequences (2001-07-24),
2. 5948611 - Primers and methods for detecting mutations in the procollagen II gene (1999-09-07),
3. 5663482 - Transgenic mice expressing a mutated human collagen gene (1997-09-02),
4. 5593859 - Synthesis of human procollagens and collagens in recombinant DNA systems (1997-01-14),
5. 5558988 - Primers and methods for detecting mutations in the procollagen II gene (1996-09-24),
6. 5405757 - Synthesis of human procollagens and collagens in recombinant DNA systems (1995-04-11),
7. 5045449 - Methods of detecting a genetic predisposition for vascular aneurysms (1991-09-03),

Title: Leena M Ala-Kokko: Innovator in Genetic Research

Introduction

Leena M Ala-Kokko is a prominent inventor based in Philadelphia, PA (US). She has made significant contributions to the field of genetic research, particularly in understanding collagen-related disorders. With a total of 7 patents, her work has paved the way for advancements in diagnostic methods for various pathological conditions.

Latest Patents

One of her latest patents focuses on compositions and methods for detecting altered COL1A1 gene sequences. This invention describes methods useful for determining whether a subject has an alteration in a gene encoding a protein chain of Type I or Type IX collagen. The patent outlines novel intronic sequences of five human genes: COL1A1, COL1A2, COL9A1, COL9A2, and COL9A3. It also provides methods for determining the existence of pathological conditions associated with altered genes, including diseases such as osteoporosis, osteoarthritis, and osteogenesis imperfecta. Additionally, her work includes primers and methods for detecting mutations in the procollagen II gene.

Career Highlights

Leena has worked at Thomas Jefferson University, where she has contributed to various research projects. Her innovative approaches have led to significant advancements in the understanding of genetic predispositions to collagen-related disorders.

Collaborations

Throughout her career, Leena has collaborated with notable professionals in her field, including Darwin J Prockop and Andrzej Fertala. These collaborations have further enhanced her research and the impact of her inventions.

Conclusion

Leena M Ala-Kokko's contributions to genetic research and her innovative patents have made a lasting impact on the field. Her work continues to influence diagnostic methods for collagen-related disorders, showcasing her dedication to advancing medical science.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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