The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 1997
Filed:
Mar. 16, 1994
Applicant:
Inventors:
Darwin J Prockop, Philadelphia, PA (US);
Leena Ala-Kokko, Philadelphia, PA (US);
Jaspal S Khillan, Philadelphia, PA (US);
Philipp Vandenberg, Philadelphia, PA (US);
Sirpa Kontusaari, Oulu, FI;
Heikki Helminen, Philadelphia, PA (US);
Anne Olsen, Moraga, CA (US);
Boris Sokolov, Philadelphia, PA (US);
Assignee:
Thomas Jefferson University, Philadelphia, PA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
800-2 ; 800D / ; 424-91 ;
Abstract
The invention is transgenic mice substantially all of whose cells contain a mutated human collagen gene. Methods for testing therapies for the treatment of osteogenesis imperfecta, osteoporosis, and chondrodysplasia are provided.