The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 1991
Filed:
Jun. 14, 1989
Leena M Ala-Kokko, Philadelphia, PA (US);
Clinton T Baldwin, Voorhees, NJ (US);
Sirpa I Kontusaari, Philadelphia, PA (US);
S Helena Kuivaniemi, Philadelphia, PA (US);
Darwin J Prockop, Philadelphia, PA (US);
Gerardus C Tromp, Philadelphia, PA (US);
Thomas Jefferson University, Philadelphia, PA (US);
Abstract
Methods of determining genetic predisposition for vascular aneurysm in mammals are disclosed. The base sequence of Type III procollagen DNA of the person tested is compared to the sequence of a standard pro.alpha.l(III) sequence. Differences in the base sequence of the test DNA indicate an increased likelihood that the person will develop vascular aneurysm. Family members of the mammal tested can also be tested to determine if they also have a genetic predisposition to vascular aneurysm by testing for the presence of the mutation in the pro.alpha.l(III) gene of the family members.