Location History:
- Signapore, SG (2022)
- Singapore, SG (2023)
Company Filing History:
3 out of 1,473 
2 out of 134 
2 out of 805 
Years Active: 2022-2025
Title: Le-Ann Hwang: Innovator in Anti-p53 Antibodies
Introduction
Le-Ann Hwang is a prominent inventor based in Singapore, known for her significant contributions to the field of biotechnology. She has been instrumental in developing innovative methods for producing antibodies that target mutant p53 polypeptides, which are crucial in cancer research and treatment. With a total of three patents to her name, her work has the potential to impact cancer diagnosis and therapy significantly.
Latest Patents
Le-Ann Hwang's latest patents focus on the development of anti-p53 antibodies. The first patent describes methods for producing an antibody that is specific for a mutant p53 polypeptide over the wildtype p53 polypeptide. This involves using an immunogen that includes a peptide or polypeptide with an antigen sequence comprising the amino acid sequence of the mutant p53 polypeptide, including the mutation and adjacent amino acids. The second patent also relates to methods for producing antibodies against mutant p53 polypeptides, specifically using the mutant p53 polypeptide as an immunogen. This patent emphasizes the use of a scaffold sequence, such as thioredoxin, to provide the antigen sequence in a solvent-accessible configuration. The antibodies generated from these methods have applications in the diagnosis, prognosis, and treatment of cancer.
Career Highlights
Le-Ann Hwang has worked with notable organizations, including the Agency for Science, Technology and Research and Singapore Health Services Pte Ltd. Her experience in these institutions has allowed her to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Le-Ann has collaborated with esteemed colleagues, including David Philip Lane and Xin Yu Koh. These partnerships have further enhanced her research and development efforts in the field of biotechnology.
Conclusion
Le-Ann Hwang is a trailblazer in the development of anti-p53 antibodies, with her innovative patents paving the way for advancements in cancer treatment and diagnosis. Her contributions to the field highlight the importance of research and collaboration in driving medical innovations forward.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.