Laurence Cocquerel-Deproy

Title: Laurence Cocquerel-Deproy: Innovator in Hepatitis E Research

Introduction

Laurence Cocquerel-Deproy is a notable inventor based in Lille, France. He has made significant contributions to the field of virology, particularly in understanding the Hepatitis E virus (HEV). His work has implications for diagnostics and treatment of viral infections.

Latest Patents

Cocquerel-Deproy holds a patent for "Hepatitis E virus ORF2 capsid polypeptides and uses thereof." This invention addresses the Hepatitis E virus, which is responsible for over 50% of acute viral hepatitis cases worldwide. The patent identifies the precise sequence of the infectious particle-associated ORF2 capsid protein. Notably, the research revealed that HEV produces three forms of the ORF2 capsid protein: ORF2i, ORF2g, and ORF2c. The ORF2i protein is linked to infectious particles, while ORF2g and ORF2c are glycoproteins not associated with infectious particles. The invention also includes antibodies specific for these proteins and diagnostic assays, such as ELISA, for diagnosing Hepatitis E virus infection.

Career Highlights

Cocquerel-Deproy has worked with prestigious institutions, including the National Center for Scientific Research (Centre National De La Recherche Scientifique) and the Regional University Hospital of Lille (Centre Hospitalier Régional Universitaire De Lille). His research has been pivotal in advancing the understanding of Hepatitis E and its associated proteins.

Collaborations

Cocquerel-Deproy has collaborated with notable colleagues, including Claire Montpellier and Jean Dubuisson. Their combined efforts have contributed to the advancements in Hepatitis E research and diagnostics.

Conclusion

Laurence Cocquerel-Deproy is a key figure in the field of virology, particularly in the study of Hepatitis E virus. His innovative work and patent contributions have the potential to enhance diagnostic methods and improve patient outcomes.