Location History:
- Bedford, MA (US) (2000)
- Essex, MA (US) (2000 - 2002)
- Rockport, MA (US) (2018)
Company Filing History:
Years Active: 2000-2018
Title: The Innovative Contributions of Lauren Sears Higgins
Introduction
Lauren Sears Higgins is a prominent inventor based in Essex, MA (US). She has made significant contributions to the field of biotechnology, holding a total of 7 patents. Her work primarily focuses on methods that enhance enzyme reactions and DNA manipulation.
Latest Patents
One of her latest patents is a method for performing multiple enzyme reactions in a single tube. This innovative approach allows for the production of a reaction mix that includes a thermolabile UDG, an AP lyase, and DNA fragments with uracil residues. The method involves incubating the reaction mix at a low temperature to cleave fragments at the uracil residues, followed by raising the temperature to inactivate the thermolabile UDG and deaminating the fragments, converting cytosine in the DNA to uracil. Another notable patent is related to the cloning and expression of MlyI restriction endonuclease and MlyI methylase, as well as BstNBII methylase in E. coli. This invention pertains to recombinant DNA that encodes these enzymes and their expression in cells containing the recombinant DNA.
Career Highlights
Lauren Sears Higgins is currently employed at New England Biolabs, Inc., where she continues to advance her research and development efforts. Her work has been instrumental in enhancing the capabilities of molecular biology techniques.
Collaborations
Some of her notable coworkers include Huimin Kong and Michael A Dalton, who have collaborated with her on various projects and research initiatives.
Conclusion
Lauren Sears Higgins is a trailblazer in the field of biotechnology, with a focus on innovative methods that improve enzyme reactions and DNA manipulation. Her contributions are paving the way for advancements in molecular biology and genetic research.