Phoenixville, PA, United States of America

Laura DeCristofano


Average Co-Inventor Count = 7.0

ph-index = 1


Company Filing History:


Years Active: 2024

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1 patent (USPTO):Explore Patents

Title: Innovations by Laura DeCristofano in Antibody Development

Introduction

Laura DeCristofano is an accomplished inventor based in Phoenixville, PA (US). She has made significant contributions to the field of biotechnology, particularly in the development of antibodies. Her innovative work focuses on creating antibodies that can selectively bind to human CD3 at acidic pH, which has important therapeutic implications.

Latest Patents

Laura holds a patent for "Antibodies binding to human CD3 at acidic pH." This invention relates to new anti-hCD3 antibodies that specifically bind to human CD3 at acidic pH, while showing minimal binding at neutral or physiological pH. The ability of these antibodies to activate T cells in acidic conditions, while having reduced activity in neutral pH, opens new avenues for therapeutic applications.

Career Highlights

Laura is currently associated with Abzyme Therapeutics LLC, where she continues to advance her research in antibody development. Her work is pivotal in enhancing the efficacy of T cell activation, which is crucial for various therapeutic strategies.

Collaborations

Laura collaborates with talented individuals such as Hiep Tran and Carla Campbell, contributing to a dynamic research environment that fosters innovation.

Conclusion

Laura DeCristofano's work in developing specialized antibodies represents a significant advancement in biotechnology. Her innovative approach has the potential to transform therapeutic applications in immunology.

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