Laura Bohn

Title: Laura Bohn: Innovator in Kappa-Opioid Research

Introduction

Laura Bohn is a prominent inventor based in Jupiter, Florida, known for her significant contributions to the field of pharmacology, particularly in the development of kappa-opioid receptor modulators. With a total of 6 patents to her name, she has made strides in creating innovative solutions for various medical conditions.

Latest Patents

Among her latest patents is the synthesis of 20-nor-salvinorin A, an analog of the kappa-opioid agonist salvinorin A. This invention provides a compound that acts as an active kappa-opioid modulator, which can be utilized in treating medical conditions where modulation of the kappa-opioid receptor is necessary. These conditions include pain, pruritis, depression, and inflammation, as well as issues related to perception and consciousness. Notably, 20-nor-salvinorin A is considered to be less addictive compared to traditional mu-opioid receptor agonists and demonstrates greater stability in vivo than its parent compound, salvinorin A. Additionally, she has developed antagonists of the kappa-opioid receptor, aimed at treating a range of disorders including addiction, anxiety disorders, and post-traumatic stress disorder.

Career Highlights

Laura Bohn has had a distinguished career, working at esteemed institutions such as The Scripps Research Institute and the University of Kansas Medical Center Research Institute. Her research has significantly advanced the understanding of kappa-opioid receptors and their potential therapeutic applications.

Collaborations

Throughout her career, Laura has collaborated with notable colleagues, including Jeffrey Aube and Kevin Frankowski, contributing to the advancement of research in her field.

Conclusion

Laura Bohn's innovative work in kappa-opioid research has the potential to transform treatment options for various medical conditions. Her contributions continue to pave the way for future advancements in pharmacology and therapeutic development.