The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2020
Filed:
Mar. 15, 2017
Applicant:
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
Thomas D. Bannister, Palm Beach Gardens, FL (US);
Laura M. Bohn, Jupiter, FL (US);
Cullen L. Schmid, Cambridge, MA (US);
Assignee:
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 31/4166 (2006.01); C07D 401/04 (2006.01); A61P 29/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/454 (2013.01); A61K 31/4166 (2013.01); A61P 29/02 (2018.01); C07D 401/04 (2013.01);
Abstract
The invention provides—opioid receptor agonists that are analgesic agents and that promote diminished side effects relative to a comparably effective dose of morphine. The side effects that are absent or attenuated include one or more of the following: constipation, respiratory depression, tolerance, dependence, nausea, confusion, sedation, hypotension, and post-treatment withdrawal symptoms.