Larry S Barak

Title: Innovator Spotlight: Larry S Barak - Pioneering GPCR Research in Durham, NC

Introduction:

Larry S Barak, a distinguished inventor based in Durham, NC, has made significant contributions to the field of G protein-coupled receptor (GPCR) research. With a portfolio of two patents at his name, Barak's innovative methods have revolutionized the detection and modification of GPCRs both in vitro and in vivo.

Latest Patents:

Barak's latest patents showcase his expertise in developing automated methods for detecting receptor activity. The first patent involves the use of conjugated proteins to track GPCR activity within cells, enabling precise localization of these proteins at endocytic vesicles and endosomes. The second patent focuses on modifying GPCRs to have altered DRY motifs, leading to constitutive desensitization and agonist-independent localization to endosomes.

Career Highlights:

Throughout his career, Larry S Barak has held pivotal roles at esteemed institutions such as the Molecular Devices Corporation and Duke University. These experiences have honed his skills in GPCR research, paving the way for groundbreaking innovations in the field of receptor biology.

Collaborations:

Barak has had the privilege of collaborating with accomplished professionals in the industry, including coworkers Robert H Oakley and Marc G Caron. Together, they have contributed to cutting-edge research and the development of novel techniques for studying GPCRs.

Conclusion:

In conclusion, Larry S Barak stands as a trailblazer in GPCR research, with a track record of innovative patents and impactful collaborations. His dedication to advancing the field of receptor biology has solidified his reputation as a visionary inventor in Durham, NC, and beyond.