Larry D Zeagler

Title: Larry D. Zeagler: Innovator in Pharmaceutical Chemistry

Introduction

Larry D. Zeagler is a notable inventor based in Corpus Christi, TX (US). He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of processes for producing enantiomeric forms of ibuprofen. With a total of 3 patents to his name, Zeagler's work has had a meaningful impact on the industry.

Latest Patents

One of Larry D. Zeagler's latest patents involves the selective precipitation of α-aryl carboxylic acid salts. This innovative process allows for the production of S(+)-ibuprofen or R(-)-ibuprofen L-lysinate salt from a mixture containing enantiomers of ibuprofen and L-lysine. The method ensures that the quantity of L-lysine does not exceed a molar equivalent of one of the enantiomers in the ibuprofen mixture. By controlling the temperature and timing, the process enables the selective precipitation of one ibuprofen enantiomer while allowing the other to precipitate out in salt form. This technique also includes a step for racemizing optically active ibuprofen through heating.

Career Highlights

Larry D. Zeagler has built a successful career at Hoechst Celanese Corporation, where he has been able to apply his expertise in pharmaceutical chemistry. His innovative approaches have contributed to advancements in drug formulation and production.

Collaborations

Throughout his career, Zeagler has collaborated with talented individuals such as Apurba Bhattacharya and John R. Fritch. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.

Conclusion

Larry D. Zeagler's contributions to pharmaceutical chemistry, particularly in the area of ibuprofen production, highlight his role as a significant inventor. His work continues to influence the industry and pave the way for future innovations.