The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 1994

Filed:

Dec. 02, 1992
Applicant:
Inventors:

Apurba Bhattacharya, Corpus Christi, TX (US);

John R Fritch, Corpus Christi, TX (US);

Carl D Murphy, Corpus Christi, TX (US);

Larry D Zeagler, Corpus Christi, TX (US);

Carina Araullo-McAdams, Corpus Christi, TX (US);

Assignee:

Hoechst Celanese Corporation, Somerville, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07B / ; C07B / ; C07C / ;
U.S. Cl.
CPC ...
5483391 ; 562401 ; 562490 ; 562492 ; 562496 ;
Abstract

There is disclosed and claimed a process whereby S(+)-ibuprofen L-lysinate salt is produced by selective precipitation from a mixture containing enantiomers of ibuprofen and L-lysine. The quantity of L-lysine is not more than about a molar equivalent of the quantity of S(+)-ibuprofen in the ibuprofen enantiomeric mixture. The mother liquors after separating the above salt are enriched in R-ibuprofen which is racemized by a novel thermal racemization process and may then be recycled.


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