Lansing J Stewart

Title: Innovations of Lansing J Stewart

Introduction: Lansing J Stewart is a notable inventor based in Bainbridge Island, WA (US). He has made significant contributions to the field of gene synthesis and protein crystallization, holding a total of six patents. His work has advanced the understanding and application of synthetic biology.

Latest Patents: One of Stewart's latest patents is for gene synthesis software. This software and its accompanying databases facilitate the design and synthesis of genes. The synthesis techniques allow for the identification, quantification, transcription, translation, and manipulation of gene sequences represented as binary code in a computing system. The software compiles user-provided constraint information to create synthetic genes that express proteins lacking disordered or variable regions. These proteins contain surface mutations that promote solubility and/or crystallization. Additionally, regions of the gene sequence that do not form stable structures can be replaced with short biological linkers to enhance protein crystallization. Another significant invention is related to screening methods for identifying ligands. This invention involves crystallization-based assays that identify ligands binding to macromolecules.

Career Highlights: Throughout his career, Lansing J Stewart has worked with various organizations, including Emerald Biostructures, Incorporated and the University of Washington. His innovative approaches have contributed to advancements in biochemistry and molecular biology.

Collaborations: Stewart has collaborated with notable individuals in his field, including Hidong Kim and Wim G J Hol. These partnerships have further enriched his research and development efforts.

Conclusion: Lansing J Stewart's contributions to gene synthesis and protein crystallization exemplify the impact of innovation in the scientific community. His patents reflect a commitment to advancing technology in synthetic biology and biochemistry.