The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2009
Filed:
Jan. 24, 2006
Lansing J. Stewart, Bainbridge Island, WA (US);
Alex Burgin, Kingston, WA (US);
John W. Walchli, Seattle, WA (US);
Kathryn Hjerrild, Bainbridge Island, WA (US);
Lansing J. Stewart, Bainbridge Island, WA (US);
Alex Burgin, Kingston, WA (US);
John W. Walchli, Seattle, WA (US);
Kathryn Hjerrild, Bainbridge Island, WA (US);
deCODE biostructures, Inc., Bainbridge Island, WA (US);
Abstract
Pieces of software and databases are used to facilitate the design and synthesis of genes. The synthesis techniques allow identification, quantification, transcription, translation, and manipulation of portions of the gene sequence represented as 0's and 1's in a computing system. These pieces of software and databases compile constraint information provided by a user to create synthetic genes to express proteins lacking disordered or variable regions and containing surface mutations that promote solubility and/or crystallization. Regions of the gene sequence that do not form stable structures can be removed and replaced by a short biological linker to improve crystallization of proteins.