Landon J Edgar

Title: Landon J Edgar: Inventor in T-Cell Immunotherapy

Introduction

Landon J Edgar is an inventor based in San Diego, California, and is associated with the Scripps Research Institute. His work includes an invention aimed at enhancing T-cell activation and expansion.

Latest Patents

Edgar is named on one patent, titled “Disruption of CD28-Sialoside Ligand Complexes to Enhance T Cell Activation.” The invention describes methods for stimulating T-cell immune responses using a targeting agent-enzyme conjugate. The conjugate combines a targeting component that binds a cell-surface molecule on T cells with a sialidase enzyme, or an enzymatically active fragment of one. The patent also describes therapeutic conjugates that pair sialidase with a T-cell-targeting antibody, such as an anti-PD1 antibody. Edgar’s listed patent portfolio includes 1 patent.

Career Highlights

Edgar’s patent work is associated with the Scripps Research Institute and focuses on a potential approach to modulating T-cell activity. The described methods and conjugates are intended to support T-cell activation, expansion, and immune responses.

Collaborations

Andrew J Thompson and Chika Kikuchi are identified as Edgar’s coworkers.

Conclusion

Landon J Edgar’s listed invention explores enzyme-targeting conjugates as a strategy for enhancing T-cell activation, reflecting his connection to immunotherapy research at the Scripps Research Institute.