Gainesville, FL, United States of America

Lakshmanan Govindasamy

USPTO Granted Patents = 11 

 

 

Average Co-Inventor Count = 4.8

ph-index = 8

Forward Citations = 201(Granted Patents)


Location History:

  • Gainesville, FL (US) (2013 - 2020)
  • Philadelphia, PA (US) (2018 - 2022)

Company Filing History:


Years Active: 2013-2025

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11 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Lakshmanan Govindasamy

Introduction

Lakshmanan Govindasamy is a prominent inventor based in Gainesville, Florida. He has made significant contributions to the field of gene therapy, particularly through his innovative work with recombinant adeno-associated virus (rAAV) vectors. With a total of 10 patents to his name, his research has paved the way for advancements in therapeutic modalities.

Latest Patents

Among his latest patents, one notable invention is the capsid-modified rAAV vector compositions and methods therefor. This patent discloses capsid-modified rAAV expression vectors, infectious virions, and pharmaceutical formulations containing them. The methods provided include preparing and using these capsid-protein-mutated rAAV constructs for various diagnostic and therapeutic applications, including as mammalian cell-targeting delivery agents and human gene therapy vectors. Additionally, he has developed large-scale production methods for these vectors, which have improved transduction efficiencies compared to unmodified rAAV vectors. Another significant patent focuses on gene therapy for treating Wilson's disease, providing compositions and regimens that utilize rAAV with a transthyretin enhancer and promoter to drive the expression of human ATP7B.

Career Highlights

Lakshmanan Govindasamy has worked with esteemed institutions such as the University of Florida Research Foundation and the University of Pennsylvania. His work has been instrumental in advancing the understanding and application of gene therapy techniques.

Collaborations

Throughout his career, he has collaborated with notable colleagues, including Li Zhong and Sergei Zolotukhin. These partnerships have contributed to the success and impact of his research.

Conclusion

Lakshmanan Govindasamy's innovative work in gene therapy and his numerous patents highlight his significant contributions to the field. His research continues to influence therapeutic strategies for various diseases, showcasing the importance of innovation in medical science.

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