Kuaile Lin

Title: Kuaile Lin: Innovator in Pharmaceutical Chemistry

Introduction

Kuaile Lin is a notable inventor based in Xinchang County, China. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the synthesis of important drug intermediates. His innovative methods have the potential to enhance the efficiency and cost-effectiveness of pharmaceutical production.

Latest Patents

Kuaile Lin holds a patent for a method for preparing a sitagliptin intermediate. The invention provides a process that involves dissolving a compound in an organic solvent and utilizing fatty acid catalysis along with chlorosilane to perform a reduction reaction of carbon-carbon double bonds. This method avoids the use of precious metals as catalysts, resulting in lower costs and simpler post-treatment processes. The product boasts a high yield, chemical purity, and optical purity, with a de % greater than 99.6%. This preparation method is suitable for industrial production and can be utilized in the synthesis of sitagliptin.

Career Highlights

Throughout his career, Kuaile Lin has worked with prominent organizations such as the Shanghai Institute of Pharmaceutical Industry and Zhejiang Medicine Co., Ltd. His experience in these institutions has allowed him to refine his skills and contribute to advancements in pharmaceutical research and development.

Collaborations

Kuaile Lin has collaborated with esteemed colleagues, including Zhengyan Cai and Jing Pan. Their combined expertise has fostered an environment of innovation and progress in their respective fields.

Conclusion

Kuaile Lin's contributions to pharmaceutical chemistry, particularly through his patented methods, highlight his role as an innovator in the industry. His work not only enhances the synthesis of vital drug intermediates but also paves the way for more efficient industrial production processes.