Company Filing History:
4 out of 129 
2 out of 215 
1 out of 985 
Years Active: 2019-2023
Title: Kotaro Yoshioka: Innovator in Nucleic Acid Technology
Introduction
Kotaro Yoshioka is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of nucleic acid technology, holding a total of six patents. His work focuses on developing low toxicity antisense nucleic acid medicines that can effectively modulate gene expression.
Latest Patents
One of his latest patents is for a nucleic acid with reduced toxicity. The objective of this invention is to provide a low toxicity antisense nucleic acid medicine that can modulate the expression of a target transcriptional product in the central nervous system and other sites of a subject. This invention includes a nucleic acid complex formed by annealing a first nucleic acid strand with an antisense oligonucleotide region and a second nucleic acid strand that is complementary to part of the first strand.
Another notable patent involves a double-stranded nucleic acid complex with overhangs. This invention provides a nucleic acid strand that can efficiently deliver an antisense oligonucleotide into the body. The complex comprises a first nucleic acid strand capable of hybridizing with a target transcription product and a second strand that includes a complementary region and at least one overhang region. This innovative approach enhances the delivery and effectiveness of the antisense oligonucleotide.
Career Highlights
Kotaro Yoshioka has worked with esteemed institutions such as Tokyo Medical and Dental University and Kumiai Chemical Industry Co., Ltd. His experience in these organizations has allowed him to advance his research and contribute to the development of groundbreaking technologies in the field of nucleic acids.
Collaborations
Throughout his career, Yoshioka has collaborated with notable colleagues, including Takanori Yokota and Kazutaka Nishina. These partnerships have fostered a collaborative environment that has led to significant advancements in their respective fields.
Conclusion
Kotaro Yoshioka is a distinguished inventor whose work in nucleic acid technology has the potential to revolutionize medical treatments. His innovative patents and collaborations highlight his commitment to advancing scientific knowledge and improving healthcare solutions.
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