Company Filing History:
18 out of 505 
3 out of 8 
3 out of 288 Years Active: 2016-2023
Title: The Innovative Contributions of Klaus Frueh in Biotechnology
Introduction
Klaus Frueh, located in Portland, OR, is an accomplished inventor in the field of biotechnology, boasting an impressive portfolio of 18 patents. His work focuses primarily on developing innovative vaccines and viral vectors, which hold promise in combating various diseases such as HIV.
Latest Patents
Frueh's latest patents reflect his commitment to advancing medical science. One of his notable inventions involves a human cytomegalovirus that comprises exogenous antigens. This invention features vectors derived from the TR strain that are ganciclovir sensitive and include essential active genes, such as US2, US3, US6, US7, and UL131A. A significant aspect of this patent is a deleterious mutation in the UL82 gene, which prevents the expression of pp71, making the vectors particularly innovative.
Additionally, Klaus Frueh's research has led to the development of HIV vaccines that incorporate one or more population episensus antigens. These vaccines are designed using the EpiGraph approach, which helps in tailoring the vaccine antigens to optimally cover the diversity within specific geographic areas. His methodologies include designing and producing vaccines that can induce an effector memory T cell response, providing a significant advancement in the fight against HIV.
Career Highlights
Throughout his career, Klaus Frueh has made substantial contributions while working with prominent organizations such as Oregon Health & Science University and Vir Biotechnology, Inc. His experience in these institutions has allowed him to collaborate with other experts in the field and further innovate in his research.
Collaborations
Frueh has worked alongside esteemed colleagues, including Louis Picker and Scott G. Hansen. These collaborations have been instrumental in enhancing the quality and impact of his research projects, allowing for a multidisciplinary approach to tackling complex health issues.
Conclusion
Klaus Frueh's work in biotechnology, underscored by his numerous patents and collaborations, highlights his significant role in advancing medical science. With a strong focus on developing effective vaccines and therapeutic methods, he continues to make invaluable contributions to public health and the fight against viral diseases.