The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2023
Filed:
Mar. 26, 2021
Applicant:
Oregon Health & Science University, Portland, OR (US);
Inventors:
Klaus Frueh, Portland, OR (US);
Scott G. Hansen, Portland, OR (US);
Jay Nelson, Lake Oswego, OR (US);
Louis Picker, Portland, OR (US);
Patrizia Caposio, Beaverton, OR (US);
Assignee:
Oregon Health & Science University, Portland, OR (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/045 (2006.01); A61K 39/12 (2006.01); C12N 15/86 (2006.01); A61K 35/33 (2015.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); C12N 15/85 (2006.01); A61K 39/21 (2006.01); C07K 14/16 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/045 (2013.01); A61K 35/33 (2013.01); A61K 39/0011 (2013.01); A61K 39/12 (2013.01); A61K 39/39 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); A61K 39/21 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/572 (2013.01); A61P 35/00 (2018.01); C07K 14/161 (2013.01); C12N 2710/16143 (2013.01); C12N 2740/15034 (2013.01); C12N 2740/16234 (2013.01);
Abstract
Human cytomegalovirus vectors comprising heterologous antigens are disclosed. The vectors derived from the TR strain, are ganciclovir sensitive, include active US2, US3, US6, US7 and UL131A genes, and have a deleterious or inactivating mutation in the UL82 gene preventing the expression of pp71.