Jay A Nelson is a prominent inventor based in Lake Oswego, Oregon. He has made significant contributions to the field of virology, particularly in the development of cytomegalovirus (CMV) vectors. With a total of 11 patents to his name, Nelson's work has advanced our understanding of immune responses and potential therapeutic applications.

Latest Patents

Among his latest patents, Nelson has developed a human cytomegalovirus comprising exogenous antigens. This innovation includes vectors derived from the TR strain that are ganciclovir sensitive. These vectors contain active US2, US3, US6, US7, and UL131A genes, along with a mutation in the UL82 gene that prevents the expression of pp71. Another notable patent involves CMV vectors that lack active UL128, UL130, UL146, and UL147 proteins. These vectors may also include microRNA regulatory elements that restrict CMV expression, allowing for the selection of different CD8+ T cell responses.

Career Highlights

Jay A Nelson is affiliated with Oregon Health & Science University, where he continues to conduct research and develop innovative solutions in the field of virology. His work has been instrumental in exploring the potential of CMV vectors for immunization and therapeutic purposes.

Collaborations

Nelson has collaborated with notable colleagues, including Louis Picker and Klaus Frueh. These partnerships have further enhanced the impact of his research and innovations.

Conclusion

Jay A Nelson's contributions to the field of virology through his patents and research at Oregon Health & Science University highlight his role as a leading inventor. His work continues to pave the way for advancements in immunology and therapeutic applications.

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