Kiyohito Shimura

Title: The Innovative Contributions of Kiyohito Shimura

Introduction

Kiyohito Shimura, an accomplished inventor based in Kanagawa, Japan, has made significant strides in the field of molecular biophotonics. With a total of three patents to his name, his work primarily focuses on advancements in antibody technology and antigen detection methodologies.

Latest Patents

Shimura’s most recent patents include groundbreaking innovations such as the "Isolated Polynucleotide encoding modified Fab' antibody, expression vector, and transformed host cell." This invention reveals an isolated polynucleotide encoding a modified Fab' antibody, which comprises an Fd chain and an L chain. Notably, the modified Fab' antibody includes a cysteine for binding to a fluorescent dye, facilitating precise detection methods.

Another significant patent is a "Method for quantitatively detecting antigen," which outlines a comprehensive five-step process. This method employs a Fab' antibody with a uniform isoelectric point modified to enhance binding and labeling with a fluorescent dye. By executing various steps, including electrophoresis and fluorescence detection, this technique allows for accurate quantification of antigens in analytical samples.

Career Highlights

Kiyohito Shimura’s career highlights include his tenure at prestigious companies such as Hamamatsu Photonics K.K. and the Laboratory of Molecular Biophotonics. His expertise in the development of biophotonic technologies has contributed to advancements that benefit research in the fields of diagnostics and treatment.

Collaborations

Throughout his career, Shimura has had the opportunity to collaborate with notable colleagues, including Kenichi Kasai and Hiroyuki Matsumoto. These collaborations have been instrumental in enhancing his research capabilities and expanding the scope of his innovative contributions.

Conclusion

Kiyohito Shimura is a remarkable inventor whose innovations in antibody and antigen detection have the potential to transform research and healthcare diagnostics. With a robust patent portfolio and collaborative spirit, he continues to pave the way for future advancements in molecular biophotonics.