Albany, CA, United States of America

Kevin J Yarema


Average Co-Inventor Count = 3.4

ph-index = 5

Forward Citations = 158(Granted Patents)


Location History:

  • Malden, MA (US) (1999)
  • Albany, CA (2002)
  • Albany, CA (US) (2000 - 2008)

Company Filing History:


Years Active: 1999-2008

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7 patents (USPTO):Explore Patents

Title: Kevin J Yarema: Innovator in Glycoconjugates and Genotoxic Agents

Introduction

Kevin J Yarema is a prominent inventor based in Albany, CA (US). He has made significant contributions to the fields of glycoconjugates and programmable genotoxic agents. With a total of 7 patents to his name, Yarema's work has the potential to impact various areas of biotechnology and medicine.

Latest Patents

One of Yarema's latest patents focuses on glycoconjugates and methods for their production. The methods involve contacting a cell with a first monosaccharide and incubating the cell under specific conditions. This process allows the cell to internalize the monosaccharide, biochemically process it into a second saccharide, and conjugate it to a carrier to form a glycoconjugate. The resulting extracellular glycoconjugate contains a selectively reactive functional group, which can be used to form products by reacting with specific agents.

Another notable patent involves programmable genotoxic agents designed to selectively kill targeted cells within a heterogeneous cell population. These compounds consist of a first agent that damages cellular DNA and a second agent that attracts a macromolecular cell component, shielding genomic lesions from repair. This innovative approach allows for the selective killing of transformed or viral-infected cells while minimizing toxicity to nonselected cells.

Career Highlights

Throughout his career, Kevin J Yarema has worked with esteemed institutions such as the University of California and the Massachusetts Institute of Technology. His research has garnered attention for its potential applications in therapeutic interventions and biotechnology.

Collaborations

Yarema has collaborated with notable scientists, including Lara K Mahal and Carolyn C Bertozzi. These partnerships have contributed to the advancement of his research and the development of innovative solutions in his field.

Conclusion

Kevin J Yarema's contributions to the fields of glycoconjugates and programmable genotoxic agents highlight his role as a leading inventor. His innovative patents and collaborations with prestigious institutions underscore the significance of his work in advancing biotechnology and medicine.

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