The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7351408 B1

PDF
Full Text
Expired
Date of Patent:
Apr. 01, 2008

Filed:

Jul. 25, 2005
Applicants:

Carolyn C. Bertozzi, Albany, CA (US);

Kevin J. Yarema, Albany, CA (US);

Lara K. Mahal, Berkeley, CA (US);

Inventors:

Carolyn C. Bertozzi, Albany, CA (US);

Kevin J. Yarema, Albany, CA (US);

Lara K. Mahal, Berkeley, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/385 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for making the functionalized glycoconjugates include (a) contacting a cell with a first monosaccharide, and (b) incubating the cell under conditions whereby the cell (i) internalizes the first monosaccharide, (ii) biochemically processes the first monosaccharide into a second saccharide, (iii) conjugates the saccharide to a carrier to form a glycoconjugate, and (iv) extracellularly expresses the glycoconjugate to form an extracellular glycoconjugate comprising a selectively reactive functional group. Methods for forming products at a cell further comprise contacting the functional group of the extracellularly expressed glycoconjugate with an agent which selectively reacts with the functional group to form a product. Subject compositions include cyto-compatible monosaccharides comprising a nitrogen or ether linked functional group selectively reactive at a cell surface and compositions and cells comprising such saccharides.


Find Patent Forward Citations

Bertozzi, Carolyn. (2008). Glycoconjugates and methods (U.S. Patent No. 7351408). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7351408

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