Kevin Dooley

Title: Kevin Dooley: Innovator in Peptide Engineering

Introduction

Kevin Dooley is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of peptide engineering, particularly in the development of calcium-dependent hydrogels. With a total of 2 patents, his work has implications in various scientific and medical applications.

Latest Patents

Kevin Dooley's latest patents focus on the innovative use of leucine beta roll domains. One of his notable inventions relates to a peptide that forms a calcium-dependent hydrogel using a rationally engineered beta roll peptide. In the absence of calcium, this peptide is intrinsically disordered. Upon the addition of calcium, the peptide adopts a corkscrew-like structure. In one embodiment, one face of the beta roll is mutated to include leucine residues. Additionally, in some embodiments, a leucine zipper forming helical domain to the engineered beta roll facilitates the formation of hydrogels through physical cross-linking in calcium-rich environments.

Career Highlights

Kevin Dooley is affiliated with Columbia University, where he continues to advance his research in peptide engineering. His work has garnered attention for its potential applications in various fields, including biotechnology and materials science.

Collaborations

Throughout his career, Kevin has collaborated with notable colleagues such as Scott Banta and Mark A Blenner. These collaborations have further enriched his research and contributed to the advancement of peptide technology.

Conclusion

Kevin Dooley stands out as an innovative inventor in the realm of peptide engineering. His contributions, particularly in the development of calcium-dependent hydrogels, showcase the potential of his research to impact various scientific fields.