Kermit M Borland

Title: Kermit M Borland: Innovator in Cell Harvesting Techniques

Introduction

Kermit M Borland is a notable inventor based in Shrewsbury, MA (US). He holds a total of 3 patents that focus on advancements in cell harvesting and processing techniques. His work has significantly contributed to the fields of biotechnology and cell biology.

Latest Patents

One of his latest patents is titled "High flow technique for harvesting mammalian cells." This invention is based on the observation that significant portions of porcine livers remain intact after standard perfusion methods. This suggests that traditional perfusion procedures do not achieve complete enzymatic digestion, resulting in lower cell recovery rates. Borland's method combines increased perfusion flow rates, occlusion of major blood vessels, extended enzymatic digestion time, and vigorous tissue dissociation techniques to achieve a uniquely high yield of viable cells.

Another significant patent is the "Method of thawing cryopreserved cells." This invention outlines a process for thawing and equilibrating cryopreserved cells at warm temperatures, specifically between 30°C and 43°C. By employing this method, the viability and metabolic activity of the cells can be improved compared to traditional cold processing methods.

Career Highlights

Throughout his career, Kermit M Borland has worked with reputable companies such as W. R. Grace Co. and Circe Biomedical, Inc. His contributions to these organizations have been instrumental in advancing their research and development efforts.

Collaborations

Borland has collaborated with notable coworkers, including Barbara A Chandler and Shawn P Cain. Their combined expertise has fostered innovation in the field of cell processing.

Conclusion

Kermit M Borland's innovative patents and career achievements highlight his significant impact on biotechnology. His work continues to influence the methods used in cell harvesting and processing, paving the way for advancements in the field.