Location History:
- Tokyo, JP (2010 - 2013)
- Ibaraki, JP (2018 - 2021)
Company Filing History:
7 out of 416 
4 out of 27 
1 out of 2 Years Active: 2010-2021
Title: Innovations and Contributions of Inventor Kentaro Enjo
Introduction
Kentaro Enjo is a prolific inventor based in Ibaraki, Japan, holding a remarkable seven patents. His innovative work primarily focuses on pharmaceutical compositions, and he has made significant contributions to the field, particularly in the treatment of nocturia.
Latest Patents
Among his latest patents is a pyridine derivative designed to address the challenges of nocturia. The inventive concept revolves around providing a compound suitable for a pharmaceutical composition specifically aimed at treating this condition. Enjo and his team hypothesized that inhibiting the nocturnal activity of placental leucine aminopeptidase (P-LAP) could help maintain and enhance endogenous arginine vasopressin (AVP) levels, leading to decreased nocturnal voids. Their research revealed that (2R)-3-amino-2-{[4-(substituted pyridine)-2-yl]methyl}-2-hydroxy-propanoic acid derivatives exhibit excellent P-LAP inhibitory activity. Through evaluations in water-loaded rats, they demonstrated that these compounds could increase endogenous AVP levels by inhibiting P-LAP, thus reducing urine production. This innovative approach positions these compounds as promising agents for treating nocturia.
Career Highlights
Throughout his career, Kentaro Enjo has been associated with notable companies in the pharmaceutical sector, including Astellas Pharma GmbH and Kotobuki Pharmaceutical Co. Ltd. His work within these organizations has been critical in advancing pharmaceutical research and development, with a focus on improving the quality of life for patients suffering from nocturia.
Collaborations
Enjo has also collaborated with distinguished colleagues such as Kenichi Kawaguchi and Akihiro Ishihata. Their combined expertise has played a pivotal role in the success of their research initiatives and has fostered a collaborative environment conducive to innovation.
Conclusion
Kentaro Enjo's contributions to the field of pharmaceuticals are significant and impactful. His innovative patents and dedicated work in treating nocturia underscore the importance of continued research and collaboration in driving advancements in healthcare. Through his efforts, Enjo not only enhances our understanding of pharmaceutical applications but also improves patient care, solidifying his status as a noteworthy inventor in his field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.