Location History:
- Chalfont, PA (US) (1995 - 2005)
- Carversville, PA (US) (2007)
Company Filing History:
Years Active: 1995-2007
Title: Innovations of Kenneth S. Koblan
Introduction
Kenneth S. Koblan is a notable inventor based in Carversville, PA (US). He has made significant contributions to the field of biotechnology, particularly in the development of humanized receptors and related assay methods. With a total of 4 patents, his work has had a considerable impact on pharmacological research.
Latest Patents
One of his latest patents involves isolated DNA molecules encoding a humanized calcitonin gene-related peptide receptor. This invention includes non-human transgenic animals and assay methods that utilize these isolated nucleic acid molecules. The humanized CGRP receptors developed by Koblan exhibit pharmacological profiles similar to the wild type human receptor, achieved through specific modifications to the mammalian RAMP1 nucleotide sequence. Another significant patent focuses on a radioligand compound that may have antiarrhythmic activity, along with methods for identifying compounds that bind to the I channel.
Career Highlights
Kenneth S. Koblan is currently associated with Merck & Company, Inc., where he continues to advance his research in pharmacology and biotechnology. His innovative work has contributed to the understanding of receptor mechanisms and their applications in medicine.
Collaborations
Throughout his career, Koblan has collaborated with esteemed colleagues, including Jackson B. Gibbs and Angus Murray MacLeod. These partnerships have fostered a collaborative environment that enhances the development of groundbreaking inventions.
Conclusion
Kenneth S. Koblan's contributions to the field of biotechnology through his patents and collaborations highlight his role as a leading inventor. His work continues to influence advancements in pharmacological research and applications.