Location History:
- Bethedsa, MD (US) (1990)
- Bethesda, MD (US) (1986 - 1994)
- Bethesa, MD (US) (1994)
Company Filing History:
7 out of 1,215 
1 out of 2,202 
Years Active: 1986-1994
Title: The Innovations of Kenneth L. Kirk
Introduction
Kenneth L. Kirk is a notable inventor based in Bethesda, MD (US), recognized for his contributions to the field of cardiovascular treatments. With a total of 8 patents, his work has significantly impacted medical research and development.
Latest Patents
One of his latest patents involves "Adenosine functionalized congeners as cardiovascular treating agents." This invention comprises a series of N.sup.6 -substituted adenosine analogues that bear functionalized chains for covalent attachment to probes or solid supports. These compounds demonstrate coronary vasodilation in the open thorax dog model, typical of A.sub.2 -adenosine receptor agonists. The potency of these compounds is modulated by distal structural changes in the chain, with the highest A.sub.2 -potency observed for two methylamides, a primary amine congener, and a biotin conjugate. These compounds exhibit antihypertensive activity, and certain components are charged, preventing them from crossing the blood-brain barrier.
Another significant patent by Kirk is related to "Azido-substituted aromatic amino acids." These azido derivatives are synthesized using tyrosine phenol-lyase and are suitable for use as photoaffinity labels and inhibitors. The formula includes various substituents that enhance their applicability in research.
Career Highlights
Throughout his career, Kenneth L. Kirk has worked with esteemed organizations, including the United States of America as represented by the Department of Health and the United States of America as represented by the Secretary of Health. His innovative work has contributed to advancements in medical treatments and pharmaceutical research.
Collaborations
Kirk has collaborated with notable individuals in his field, including Kenneth Alan Jacobson and John W. Daly. These partnerships have fostered a collaborative environment that has led to significant advancements in their respective research areas.
Conclusion
Kenneth L. Kirk's contributions to cardiovascular treatments and his innovative patents highlight his importance in the field of medical research. His work continues to influence advancements in healthcare and pharmaceutical development.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.