The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 1992
Filed:
Mar. 15, 1988
Applicant:
Inventors:
Kenneth A Jacobson, Silver Spring, MD (US);
Kenneth L Kirk, Bethesda, MD (US);
David C Furlano, Bethesda, MD (US);
Yechiel Shai, Silver Spring, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; C07D / ; C07H / ;
U.S. Cl.
CPC ...
530303 ; 530345 ; 424-11 ; 536 26 ; 544271 ; 544276 ; 560 41 ; 562438 ; 564184 ; 564185 ;
Abstract
Radioactive fluorine can be easily introduced into biologically active molecules containing amino groups. A p-bromomethyl benzoyl group is coupled to the amino group of the biologically active molecule, and bromine is displaced by fluorine. Alternatively, the bromine on the bromomethylbenzoyl group is first displaced by fluorine, and the fluoromethyl benzoyl group is then coupled to the amino group of the biologically active molecule. The compounds so produced are useful in diagnostic nuclear medicine.