Location History:
- Hirakata, JP (1997)
- Osaka, JP (1995 - 1998)
Company Filing History:
Years Active: 1995-1998
Title: Ken Okabayashi: Innovator in Yeast Biotechnology
Introduction
Ken Okabayashi is a distinguished inventor based in Osaka, Japan. He holds a significant portfolio of four patents that revolve around advancements in yeast biotechnology. His work focuses on the development of innovative plasmids and mutant strains that enhance protein production processes.
Latest Patents
Ken Okabayashi's latest patents include a groundbreaking albumin gene-containing plasmid designed for use in yeast hosts. This plasmid integrates vital components such as a yeast-derived promoter and an albumin-encoding region, allowing for efficient gene expression within the yeast cells. Importantly, it is constructed to be integrated into the yeast host chromosomal sequence, ensuring that it cannot replicate autonomously in yeast environments. In addition to this, he has developed a yeast host transformed with this plasmid, along with a method for producing albumin by cultivating the transformant.
Another notable invention is a mutant strain of Pichia pastoris that utilizes methanol alongside glucose for growth. This methylotrophic and glucotrophic strain can produce heterologous proteins efficiently through simultaneous growth and protein production processes in culture. This innovation enables the large-scale production of proteins within a short timeframe, making significant strides in biotechnological applications.
Career Highlights
Ken Okabayashi is currently affiliated with The Green Cross Corporation, where his research contributes to advancements in biotechnology. His expertise in yeast systems and plasmid design informs the development of novel methods that improve efficiency and output in protein manufacturing.
Collaborations
Throughout his career, Okabayashi has collaborated with talented colleagues, including Haruhide Kawabe and Naofumi Hayasuke. These partnerships have fostered an environment of continued innovation and shared knowledge, resulting in several successful projects in the field of biotechnology.
Conclusion
Ken Okabayashi exemplifies the spirit of innovation in the biotechnology sector. His contributions, marked by multiple patents, underscore the importance of yeast systems in modern protein production. As he continues to develop new methodologies and enhance existing technologies, Okabayashi remains a pivotal figure in advancing the scientific community's understanding of yeast biotechnology.