Keming Song

Title: The Innovative Contributions of Keming Song

Introduction

Keming Song is a notable inventor based in Ballwin, MO (US). He has made significant contributions to the field of molecular biology, particularly in the area of nucleic acid amplification. With a total of 4 patents to his name, his work has advanced the understanding and application of genetic materials.

Latest Patents

Keming Song's latest patents include innovative processes for directionally ligating double-stranded nucleic acids. These patents provide amplification mixtures, kits, and processes for amplifying nucleic acids. Specifically, they utilize an amplification mixture that comprises a polymerase, a deoxynucleotidetriphosphate (dNTP) mixture containing modified dNTPs, and both a first and second primer. The dNTP mixtures are designed to include modified dNTPs for at least two of the four nucleotide triphosphates. When incorporated into a polynucleotide, these modified dNTPs impart resistance to enzymatic degradation by an exonuclease at the sites of incorporation. Additionally, the patents cover the amplicons and vectors that incorporate these modified nucleotides.

Career Highlights

Throughout his career, Keming Song has worked with prominent companies such as Ortho-Clinical Diagnostics, Inc. and Sigma-Aldrich Co. LLC. His experience in these organizations has contributed to his expertise in the field of biotechnology and molecular diagnostics.

Collaborations

Keming Song has collaborated with notable colleagues, including David R. Patterson and Jeffrey M. Linnen. These collaborations have likely enriched his research and development efforts, leading to innovative solutions in his field.

Conclusion

Keming Song's contributions to the field of molecular biology through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the scientific community and advance the understanding of nucleic acids.