Company Filing History:
2 out of 1,290 
2 out of 5 Years Active: 2022-2024
Title: The Innovative Contributions of Keith M Connolly
Introduction
Keith M Connolly is a prominent inventor based in Cambridge, MA. He has made significant contributions to the field of gene editing through his innovative work on modified CAS9 proteins. With a total of 2 patents, Connolly's inventions are paving the way for advancements in genetic research and applications.
Latest Patents
Connolly's latest patents focus on a mutant SaCas9 protein. This protein features a unique amino acid sequence resulting from several mutations, including changes at positions 782, 800, 968, 985, 991, 1021, 927, 929, and 1017. These modifications allow the protein to relax restrictions on target sequences while maintaining its binding ability to guide RNA. This innovation is particularly useful as a tool for gene editing, enhancing the precision and effectiveness of genetic modifications.
Career Highlights
Throughout his career, Connolly has worked with esteemed institutions, including the University of Tokyo and Modalis Therapeutics Corporation. His experience in these organizations has contributed to his expertise in the field of genetic engineering and biotechnology.
Collaborations
Connolly has collaborated with notable scientists such as Osamu Nureki and Hiroshi Nishimasu. These partnerships have further enriched his research and development efforts in gene editing technologies.
Conclusion
Keith M Connolly's work in developing modified CAS9 proteins represents a significant advancement in gene editing. His contributions are expected to have a lasting impact on the field of genetics and biotechnology.