Location History:
- Takasaki, JP (1998 - 2003)
- Gunma, JP (2006 - 2015)
Company Filing History:
5 out of 215 
3 out of 272 
1 out of 42 Years Active: 1998-2015
Title: Kazuhiro Motoki: Innovator in Antibody Technology
Introduction
Kazuhiro Motoki is a prominent inventor based in Takasaki, Japan. He has made significant contributions to the field of biotechnology, particularly in the development of therapeutic antibodies. With a total of 9 patents to his name, Motoki's work has the potential to impact medical treatments significantly.
Latest Patents
One of Motoki's latest inventions is an agonist antibody to the human thrombopoietin receptor, also known as human c-Mpl. This invention provides a pharmaceutical composition for the treatment of thrombocytopenia. The disclosed agonist antibody comprises antibody constant regions, which may contain domain substitutions, deletions, substitutions, additions, or insertions of amino acid residues. Additionally, it includes antibody variable regions capable of binding to and activating the human thrombopoietin receptor. This agonist antibody induces colony formation at a concentration of 10,000 ng/ml or lower and exhibits maximal activity at least 50% higher than that of PEG-rHuMGDF, with an effective concentration (EC50) of 100 nM or less.
Career Highlights
Throughout his career, Kazuhiro Motoki has worked with notable companies such as Kirin Beer and Kyowa Hakko Kirin Co., Limited. His experience in these organizations has contributed to his expertise in antibody technology and pharmaceutical development.
Collaborations
Motoki has collaborated with esteemed colleagues, including Yasuhiko Koezuka and Koji Kabaya. These partnerships have likely enhanced his research and innovation capabilities.
Conclusion
Kazuhiro Motoki is a distinguished inventor whose work in antibody technology holds promise for advancing medical treatments. His contributions to the field are noteworthy, and his patents reflect his commitment to innovation in biotechnology.