Company Filing History:
Years Active: 1998-2011
Title: Kayo Inaba: Innovator in Immunology
Introduction
Kayo Inaba is a prominent inventor based in Kyoto, Japan. She has made significant contributions to the field of immunology, particularly in the development of methods for utilizing apoptotic cells in antigen delivery. With a total of 7 patents, her work has the potential to advance vaccine therapies and treatments for autoimmune diseases.
Latest Patents
One of her latest patents is titled "Methods for use of apoptotic cells to deliver antigen to dendritic cells for induction or tolerization of T cells." This invention focuses on methods and compositions that effectively deliver antigens to dendritic cells, which are crucial for inducing antigen-specific cytotoxic T lymphocytes and T helper cells. The invention also includes assays for evaluating the activity of cytotoxic T lymphocytes. By targeting antigens to dendritic cells through apoptotic cells, which can be modified to express non-native antigens, the invention enhances the ability of dendritic cells to process and present these antigens, thereby inducing cytotoxic T lymphocyte activity and contributing to vaccine therapies.
Another significant patent is the "Method for in vitro proliferation of dendritic cell precursors and their use to produce immunogens." This method provides a way to produce proliferating cultures of dendritic cell precursors and subsequently mature dendritic cells in culture. The mature dendritic cells can be used to create novel T cell dependent antigens, which may serve as immunogens for vaccines or treatments for diseases, including autoimmune conditions such as juvenile diabetes and multiple sclerosis.
Career Highlights
Kayo Inaba has worked at prestigious institutions, including The Rockefeller University. Her research has been pivotal in advancing our understanding of dendritic cells and their role in the immune response.
Collaborations
Throughout her career, Kayo has collaborated with notable scientists, including Ralph M. Steinman and Gerold Schuler. These collaborations have further enriched her research and contributions to immunology.
Conclusion
Kayo Inaba's innovative work in immunology, particularly her patents related to dendritic cells and antigen delivery, showcases her significant impact on the field. Her contributions hold promise for the development of new therapeutic strategies and vaccines.