Karolis Matjosaitis

Title: **Karolis Matjosaitis: Innovating in DNA Polymerase Research**

Introduction

Karolis Matjosaitis is a prominent inventor based in Vilnius, Lithuania, recognized for his significant contributions to the field of biotechnology. With a notable portfolio comprising two patents, he has established himself as an innovator in the realm of DNA polymerases, specifically focusing on thermophilic enzymes.

Latest Patents

Matjosaitis's latest patents pertain to thermophilic DNA polymerase mutants. These innovations are centered around family B DNA polymerases that include a neutral amino acid residue positioned near the C-terminus of the catalytic domain. This particular position corresponds to a basic amino acid residue found in the wild-type Pfu polymerase. The patents also detail related uses, methods, and compositions of these mutants. In various instances, the polymerases feature a 3'-5' exonuclease domain and/or a sequence non-specific dsDNA binding domain, enhancing their utility in genetic research and applications.

Career Highlights

Currently, Matjosaitis is affiliated with Thermo Fisher Scientific Baltics UAB, a leading company in the area of scientific solutions. His work there emphasizes advancing the capabilities of DNA polymerases for more efficient and effective molecular biology applications.

Collaborations

Throughout his career, Matjosaitis has collaborated with esteemed colleagues including Remigijus Skirgaila and Renata Rimseliene. Together, they have contributed to various projects that aim to push the boundaries of biotechnological innovations.

Conclusion

Karolis Matjosaitis exemplifies the spirit of innovation within the scientific community. With his groundbreaking work on thermophilic DNA polymerase mutants, he continues to pave the way for advancements in genetic research, showcasing the impact of dedicated inventors in the biotechnological landscape.