Location History:
- Potomac, MD (US) (1998 - 2017)
- Sunny Isles, FL (US) (2017)
- Hallandale Beach, FL (US) (2019 - 2020)
Company Filing History:
21 out of 23 
3 out of 3 
3 out of 15,579 
Years Active: 1998-2020
Title: Karl K. Johe: Innovator in Neural Stem Cell Technology
Introduction
Karl K. Johe is a prolific inventor based in Potomac, MD, holding an impressive 25 patents to his name. His groundbreaking work in the field of neuroscience and stem cell technology has made significant contributions to the understanding and treatment of neurodegenerative diseases.
Latest Patents
Among his latest patents, one titled "Stable neural stem cells comprising an exogenous polynucleotide coding for a growth factor and methods of use thereof" showcases human neural stem cells that integrate an exogenous polynucleotide coding for a growth factor, such as IGF-1. This innovation presents promising methods for utilizing these stem cells in treating neurodegenerative disorders, including Amyotrophic Lateral Sclerosis (ALS). Another notable patent focuses on the "Amelioration of certain deficiencies due to stroke," whereby the treatment is aimed at mitigating the motor skill and cognitive deficits that arise after a stroke through the use of pharmaceutically acceptable salts of 2-amino substituted nicotinamides.
Career Highlights
Karl K. Johe has made significant strides in his career by working with leading biotechnology firms such as Neuralstem, Inc. and Neuralstem Biopharmaceuticals Ltd. His endeavors in these companies have further advanced research in neural stem cell applications and the formulation of treatment protocols for neurological conditions.
Collaborations
Throughout his career, Karl has collaborated with esteemed colleagues, including Thomas Hazel and Judith Kelleher-Andersson. These collaborations have enriched his research, fostering innovation in techniques and methodologies in the evolving field of neural science.
Conclusion
In conclusion, Karl K. Johe stands out as a key figure in the advancement of therapeutic options for neurodegenerative diseases. His academic and professional journey not only highlights his dedication to neuroscience but also depicts the impactful contributions of his patents, which pave the way for future innovations in the health sector.