The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2016
Filed:
Apr. 15, 2009
Applicants:
Renji Yang, Silver Spring, MD (US);
Karl K. Johe, Potomac, MD (US);
Inventors:
Renji Yang, Silver Spring, MD (US);
Karl K. Johe, Potomac, MD (US);
Assignee:
Neuralstem, Inc., Rockville, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/22 (2006.01); C12N 5/0797 (2010.01); A61K 35/30 (2015.01); G01N 33/50 (2006.01); C12N 5/16 (2006.01); C12N 5/0793 (2010.01); G01N 33/94 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
G01N 33/5058 (2013.01); A61K 35/30 (2013.01); C12N 5/0619 (2013.01); C12N 5/0623 (2013.01); C12N 5/16 (2013.01); G01N 33/502 (2013.01); G01N 33/5008 (2013.01); G01N 33/5073 (2013.01); G01N 33/9413 (2013.01); A61K 35/12 (2013.01); C12N 2500/25 (2013.01); C12N 2500/90 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/13 (2013.01); C12N 2501/148 (2013.01); C12N 2501/392 (2013.01); C12N 2501/395 (2013.01); C12N 2501/91 (2013.01); C12N 2506/02 (2013.01); C12N 2510/00 (2013.01); C12N 2510/02 (2013.01);
Abstract
A systematic and efficient method for establishing stable neural stem cell lines and neuronal progenitor lines is described. The resulting cell lines provide robust, simple, and reproducible cultures of human and other mammalian neurons in commercially useful mass quantities while maintaining normal karyotypes and normal neuronal phenotypes.