Company Filing History:
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1 out of 1 Years Active: 2009-2011
Title: The Innovations of Karl Dean
Introduction
Karl Dean is an accomplished inventor based in Marlborough, MA (US). He has made significant contributions to the field of chemistry, particularly in the development of novel compounds with antimicrobial properties. With a total of 2 patents to his name, Dean's work has the potential to impact various applications in medicine.
Latest Patents
One of Karl Dean's latest patents involves N-formyl hydroxylamine compounds. These compounds are characterized by their formula I, which includes N-formyl hydroxylamines and their derivatives. The invention discloses that these N-formyl hydroxylamine compounds inhibit peptidyl deformylase (PDF), an enzyme found in prokaryotes. This inhibition is crucial as it provides a pathway for developing new antimicrobials and antibiotics. The compounds exhibit selective inhibition of peptidyl deformylase compared to other metalloproteinases, such as MMPs. Additionally, the patent outlines methods for the preparation and use of these innovative compounds.
Career Highlights
Throughout his career, Karl Dean has worked with notable companies in the pharmaceutical industry, including Novartis AG and Vicuron Pharmaceuticals Inc. His experience in these organizations has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Some of Karl Dean's coworkers include Kathryn Rene Bracken and Simon Bushell. Their collaborative efforts have likely played a role in advancing the research and development of the compounds he has patented.
Conclusion
Karl Dean's innovative work in the field of chemistry, particularly with N-formyl hydroxylamine compounds, showcases his dedication to advancing antimicrobial research. His contributions have the potential to lead to significant advancements in medical treatments.