Karen Leirs

Title: Inventor Spotlight: Karen Leirs

Introduction

Karen Leirs is an innovative inventor based in Oud-Heverlee, Belgium. With a notable portfolio comprising two patents, she has made significant strides in the realm of sample analysis. Her work primarily emphasizes methods and devices designed for detecting target analytes, showcasing her expertise in applying digital microfluidics technology.

Latest Patents

Karen's latest patents revolve around advanced techniques for sample analysis. One of her key inventions describes methods for detecting target analytes utilizing an array of wells, a technique particularly beneficial for identifying low concentrations of these analytes. A major challenge of using an array of wells is the need to seal them effectively. To address this, Karen's method employs digital microfluidics to seal the wells with a fluid that is immiscible with the aqueous liquid present, thereby preventing evaporation and contamination during signal analysis. The inventive process involves generating a biphasic droplet consisting of both the immiscible fluid and an aqueous fluid. By electrically actuating the aqueous fluid, the immiscible fluid is maneuvered to create a secure seal over the wells, ensuring precise and reliable sample analysis.

Career Highlights

Throughout her career, Karen has been associated with esteemed organizations such as Abbott Laboratories Corporation and Katholieke Universiteit Leuven. Her contributions in these institutions demonstrate her commitment to innovation and excellence in the field of scientific research.

Collaborations

In addition to her impressive work, Karen has collaborated with notable colleagues, including Mark A. Hayden and Elena Pérez-Ruiz. These partnerships have played an essential role in the development of her patented technologies and the advancement of research processes in her area of expertise.

Conclusion

Karen Leirs stands out as a remarkable inventor whose contributions to sample analysis technology are influential in the scientific community. With her innovative spirit and dedication, she continues to push the boundaries of what is possible in her field, paving the way for future advancements that can drive significant improvements in the detection and analysis of target analytes.