The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2023
Filed:
May. 23, 2019
Abbott Laboratories, Abbott Park, IL (US);
The Katholieke Universiteit Leuven (Ku Leuven), Waaistraat, BE;
Mark A. Hayden, Ingleside, IL (US);
Karen Leirs, Oud-Heverlee, BE;
Elena Pérez-Ruiz, Woluwe Saint Lambert, BE;
Jeroen Lammertyn, Neerijse, BE;
Abbott Laboratories, Abbott Park, IL (US);
The Katholieke Universiteit Leuven, Waistraat, BE;
Abstract
Methods for detecting target analytes utilizing an array of wells are advantageous for detection of low concentrations of target analytes. Use of an array of wells requires sealing of the wells. The methods provided herein utilize digital microfluidics to seal wells of an array with a fluid that is immiscible with the aqueous liquid present in the wells to prevent evaporation and contamination of the aqueous fluid during analysis of signals from the wells. The disclosed method include generating a biphasic droplet composed of the immiscible fluid and an aqueous fluid. The immiscible fluid present in the biphasic droplet is moved over the array of wells to seal the wells by electrically actuating the aqueous fluid present in the biphasic droplet which in turn pulls the immiscible fluid.