Location History:
- Philadelphia, PA (US) (1997 - 2005)
- Bala Cynwyd, PA (US) (2007 - 2024)
Company Filing History:
6 out of 2,620 
3 out of 8 
2 out of 8,384 
Years Active: 1997-2024
Title: The Innovative Contributions of Karen Kozarsky
Introduction
Karen Kozarsky is a prominent inventor based in Bala Cynwyd, PA (US). She has made significant contributions to the field of gene therapy, particularly in the treatment of genetic disorders. With a total of 10 patents to her name, her work has the potential to impact many lives.
Latest Patents
Kozarsky's latest patents include groundbreaking methods to treat mucopolysaccharidosis type II, utilizing a recombinant adeno-associated virus (AAV) vector that encodes iduronate-2-sulfatase. Another notable patent describes a method to prevent, inhibit, or treat symptoms associated with central nervous system diseases by administering a rAAV encoding a gene product. Additionally, she has developed techniques for injecting single-stranded or self-complementary AAV into the cerebrospinal fluid, demonstrating different cellular tropisms in the central nervous system. These innovations allow for targeted treatment of specific cells, enhancing the effectiveness of gene therapy.
Career Highlights
Throughout her career, Kozarsky has worked with esteemed institutions such as the University of Pennsylvania and Regenxbio Inc. Her research has focused on advancing gene therapy techniques, particularly for conditions that currently have limited treatment options.
Collaborations
Kozarsky has collaborated with notable colleagues, including James M. Wilson and Jerome Frank Strauss III. These partnerships have fostered a collaborative environment that enhances the development of innovative therapies.
Conclusion
Karen Kozarsky's contributions to the field of gene therapy exemplify the impact of innovative thinking in medicine. Her patents and research continue to pave the way for new treatments that could significantly improve patient outcomes.