The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Sep. 27, 2017
Applicants:

Regents of the University of Minnesota, Minneapolis, MN (US);

Regenxbio Inc., Rockville, MD (US);

Inventors:

R. Scott McIvor, St. Louis Park, MN (US);

Lalitha R. Belur, St. Paul, MN (US);

Walter Low, Shorewood, MN (US);

Carolyn Fairbanks, St. Paul, MN (US);

Karen Kozarsky, Bala Cynwyd, PA (US);

Assignees:

Regents of the University of Minnesota, Minneapolis, MN (US);

REGENXBIO Inc., Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 38/43 (2006.01); A61K 38/47 (2006.01); A61K 48/00 (2006.01); C12N 7/00 (2006.01); C12N 15/00 (2006.01); C12N 15/113 (2010.01); C12N 15/52 (2006.01); C12N 15/85 (2006.01); C12N 15/86 (2006.01); C12N 15/861 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 48/00 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14171 (2013.01); C12N 2830/007 (2013.01); C12Y 302/01076 (2013.01);
Abstract

A method to prevent, inhibit or treat one or more symptoms associated with a disease of the central nervous system by intrathecally, intracerebroventricularly or endovascularly administering a rAAV encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease.


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