Karel Blaha

Title: Karel Blaha - Innovator in Sorbent Technology

Introduction

Karel Blaha is a notable inventor based in Prague, Czech Republic. He has made significant contributions to the field of sorbent technology, particularly through his innovative patent. His work focuses on the development of specific sorbents that have practical applications in affinity chromatography.

Latest Patents

Karel Blaha holds a patent for a specific sorbent having a D-aminoacid moiety covalently bonded to a solid. This invention relates to specific sorbents based on hydrophilic polymeric gels, preferably of a macroporous character. These sorbents carry covalently bonded D-aminoacids or peptides that contain D-aminoacid units. The basic carrier is prepared by copolymerization of hydroxyalkyl esters or hydroxyalkylamides of acrylic and methacrylic acid with crosslinking acrylate or methacrylate comonomers. The resulting sorbents are used as insolubilized inhibitors in the affinity chromatography of proteolytic enzymes, demonstrating mechanical and hydrolytical stability.

Career Highlights

Karel Blaha is associated with the Czech Academy of Sciences, where he has been involved in various research projects. His work has led to advancements in the field of biochemistry and materials science. His innovative approach to sorbent technology has garnered attention in scientific communities.

Collaborations

Karel has collaborated with notable colleagues such as Jiri Coupek and Jaroslava Turkova. These collaborations have contributed to the development and refinement of his patented technologies.

Conclusion

Karel Blaha's contributions to sorbent technology through his innovative patent highlight his role as a significant inventor in the field. His work continues to influence advancements in affinity chromatography and related applications.