Company Filing History:
3 out of 4 
3 out of 950 
1 out of 167 
Years Active: 2005-2012
Title: Kaoru Otsuka: Innovator in Smooth Muscle Cell Research
Introduction
Kaoru Otsuka is a prominent inventor based in Saitama, Japan. He has made significant contributions to the field of biotechnology, particularly in the study of smooth muscle cell differentiation. With a total of 7 patents to his name, Otsuka's work has the potential to impact drug development for various diseases.
Latest Patents
One of Otsuka's latest patents involves an antibody directed to a protein that plays a crucial role in maintaining the differentiation of smooth muscle cells. This invention was developed through a culture system of chicken gizzard smooth muscle cells, utilizing the differential display method and subtracted hybridization method. The cDNA sequence obtained was used to identify a novel gene, 'C-NT2RP3001495', which encodes a protein with two WW domains that are essential for protein interactions. This protein is believed to regulate intracellular signal transduction and gene expression, making it valuable for developing drugs targeting diseases related to smooth muscle cell differentiation. Another significant patent includes the isolation of novel full-length cDNAs derived from humans, which provide essential information for analyzing polypeptide functions.
Career Highlights
Throughout his career, Otsuka has worked with notable organizations such as the Research Association for Biotechnology and Chugai Seiyaku Kabushiki Kaisha. His research has been instrumental in advancing our understanding of smooth muscle cell biology and its implications for health.
Collaborations
Otsuka has collaborated with esteemed colleagues, including Takao Isogai and Tomoyasu Sugiyama. These partnerships have further enriched his research and contributed to the success of his innovative projects.
Conclusion
Kaoru Otsuka's work exemplifies the impact of innovation in biotechnology, particularly in the realm of smooth muscle cell research. His patents and collaborations highlight his commitment to advancing medical science and improving health outcomes.