Company Filing History:
Years Active: 2022-2024
Title: Kan Handa: Innovator in Genetic Engineering and Stem Cell Research
Introduction
Kan Handa is a prominent inventor based in Pittsburgh, PA (US), known for his significant contributions to the field of genetic engineering and stem cell research. With a total of 2 patents, Handa has made strides in developing innovative methods for producing human induced pluripotent stem cells (iPSCs) and engineering them for various applications.
Latest Patents
One of Handa's latest patents focuses on "Human induced pluripotent stem cells for high efficiency genetic engineering." This patent discloses methods for efficiently generating iPSCs that contain a nucleic acid with a doxycycline promoter linked to a nucleic acid encoding Cas9. The methods involve transfecting human somatic cells with a specific nucleic acid molecule and inducing these cells to form iPSCs, which can then undergo CRISPR/Cas9-mediated recombination at high efficiency. The cultured iPSCs can be used to target any gene of interest by introducing nucleic acids encoding sgRNAs.
Another notable patent by Handa is related to "Methods of engineering human induced pluripotent stem cells to produce liver tissue." This patent outlines methods for producing human hepatocytes from iPSCs and includes the development of transgenic rats for the expansion of these human hepatocytes.
Career Highlights
Kan Handa is affiliated with the University of Pittsburgh, where he conducts his research and development in the field of stem cell technology. His work has garnered attention for its potential applications in regenerative medicine and genetic therapies.
Collaborations
Throughout his career, Handa has collaborated with notable colleagues, including Alejandro Soto-Gutierrez and Alexandra Sylvie Collin De l'Hortet. These collaborations have further enhanced the impact of his research in the scientific community.
Conclusion
Kan Handa is a distinguished inventor whose work in genetic engineering and stem cell research continues to pave the way for advancements in medical science. His innovative patents reflect his commitment to improving human health through cutting-edge technology.