The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
Feb. 13, 2018
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Alejandro Soto-Gutierrez, Pittsburgh, PA (US);
Tomoji Mashimo, Osaka, JP;
Alexandra Sylvie Collin de l'Hortet, Pittsburgh, PA (US);
Eduardo Cervantes Alvarez, Huixquilucan, MX;
Jorge Guzman Lepe, Pittsburgh, PA (US);
Kan Handa, Pittsburgh, PA (US);
Kazuki Takeishi, Pittsburgh, PA (US);
Yang Wang, Pittsburgh, PA (US);
Branimir Popovic, Pittsburgh, PA (US);
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Abstract
Methods are disclosed herein for producing human hepatocytes from human induced pluripotent stem cells. Also provided are transgenic rats for the expansion of human hepatocytes, such as those produced using the methods disclosed herein.